Cinacalcet HCl

CAS 364782-34-3

General Information

Cinacalcet hydrochloride is a calcimimetic agent, meaning that it mimics the action of calcium. It is used to treat elevated calcium levels in the blood in the following disorders: secondary hyperparathyroidism (HPT) in patients with chronic kidney disease on dialysis; hypercalcemia in patients with parathyroid carcinoma; and severe hypercalcemia in patients with primary hyperparathyroidism who are unable to undergo parathyroidectomy.

About the API

Systematic name N-[1-(R)-(-)-(1-naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]-1-aminopropane hydrochloride
Trade name(s) Sensipar, Mimpara
Technology Synthetic
Molecular Formula C22H22F3N•HCl
Molecular Weight 393.9 g/mol
Physical properties crystalline solid
Therapeutic category Endocrinology
Available formulations Oral Solid
Regulations EU DMF Flag EU DMF US DMF Flag US DMF