General Information
Cinacalcet hydrochloride is a calcimimetic agent, meaning that it mimics the action of calcium. It is used to treat elevated calcium levels in the blood in the following disorders: secondary hyperparathyroidism (HPT) in patients with chronic kidney disease on dialysis; hypercalcemia in patients with parathyroid carcinoma; and severe hypercalcemia in patients with primary hyperparathyroidism who are unable to undergo parathyroidectomy.
About the API
Systematic name
N-[1-(R)-(-)-(1-naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]-1-aminopropane hydrochloride
Trade name(s)
Sensipar, Mimpara
Technology
Synthetic
Molecular Formula
C22H22F3N•HCl
Molecular Weight
393.9 g/mol
Physical properties
crystalline solid
Therapeutic category
Endocrinology
Available formulations
Oral Solid
Regulations
EU DMF
US DMF
EU DMF
US DMF