General Information
Megestrol acetate is a synthetic derivative of the hormone progesterone, which is naturally produced in the body. The mechanism of action of megestrol involves binding to progesterone receptors, acting as an agonist (activator) of these receptors. By binding to these receptors, megestrol exerts progestational effects on various tissues in the body. In its finished dose form, Megestrol acetate is administered orally to treat anorexia and cachexia or serious unexplained weight loss and is also used as an antineoplastic agent to treat certain types of cancer.
About the API
Systematic name
[(8R,9S,10R,13S,14S,17R)-17-acetyl-6,10,13-trimethyl-3-oxo-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate
Trade name(s)
Megace
Technology
High Potent
Molecular Formula
C24H32O4
Molecular Weight
384.5 g/mol
Therapeutic category
Endocrinology
Available formulations
Oral Liquid
Oral Solid
Regulations
CEP
EU DMF
US DMF
CEP
EU DMF
US DMF