Megestrol acetate

CAS 595-33-5

General Information

Megestrol acetate is a synthetic derivative of the hormone progesterone, which is naturally produced in the body. The mechanism of action of megestrol involves binding to progesterone receptors, acting as an agonist (activator) of these receptors. By binding to these receptors, megestrol exerts progestational effects on various tissues in the body. In its finished dose form, Megestrol acetate is administered orally to treat anorexia and cachexia or serious unexplained weight loss and is also used as an antineoplastic agent to treat certain types of cancer.

About the API

Systematic name [(8R,9S,10R,13S,14S,17R)-17-acetyl-6,10,13-trimethyl-3-oxo-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate
Trade name(s) Megace
Technology High Potent
Molecular Formula C24H32O4
Molecular Weight 384.5 g/mol
Therapeutic category Endocrinology
Available formulations Oral Liquid Oral Solid
Regulations CEP Flag CEP EU DMF Flag EU DMF US DMF Flag US DMF