General Information
Sofosbuvir is an antiviral agent used in combination with other drugs to treat patients with chronic hepatitis C (CHC), a life threatening liver disease. CHC results from infection by the hepatitis C virus.
About the API
Systematic name
(S)-Isopropyl 2-((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)-(phenoxy)phosphorylamino)propanoate)
Trade name(s)
Sovaldi
Technology
Synthetic
Molecular Formula
C22H29FN3O9P
Molecular Weight
529.45 g/mol
Physical properties
white to off-white crystalline solid
Therapeutic category
Antiviral
Available formulations
Oral Solid
Regulations
US DMF
US DMF