Pemetrexed Diacid

CAS 357166-30-4

General Information

Pemetrexed is a drug that belongs to a class of molecules termed folate antimetabolites and is used in the treatment of aggressive and late stage cancers. Pemetrexed inhibits three enzymes involved in the folate pathway: thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT).

About the API

Systematic name (2S)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid
Trade name(s) Alimta
Technology High Potent
Molecular Formula C20H21N5O6
Molecular Weight 427.41 g/mol
Physical properties White to off-white solid
Therapeutic category Oncology
Available formulations Injectables
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