Omeprazole

CAS 73590-58-6

About the API

Technology Synthetic Organic Chemistry
Therapeutic category Gastroenterology
Available formulations Injectables Oral Liquid Oral Solid Oral Solid Long-Acting
Regulations CEP Flag CEP EU DMF Flag EU DMF Japan DMF Flag Japan DMF US DMF Flag US DMF

Mechanism of action

Omeprazole belongs to a class of antisecretory compounds, the substituted benzimidazoles, that suppress gastric acid secretion by specific inhibition of the H+/K+ ATPase enzyme system at the secretory surface of the gastric parietal cell. Because this enzyme system is regarded as the acid pump within the gastric mucosa, omeprazole has been characterized as a gastric acid-pump inhibitor. This effect is dose-related and leads to inhibition of both basal and stimulated acid secretion irrespective of the stimulus.