Omeprazole

Omeprazole belongs to a class of antisecretory compounds, the substituted benzimidazoles, that suppress gastric acid secretion by specific inhibition of the H+/K+ ATPase enzyme system at the secretory surface of the gastric parietal cell. Because this enzyme system is regarded as the acid pump within the gastric mucosa, omeprazole has been characterized as a gastric acid-pump inhibitor. This effect is dose-related and leads to inhibition of both basal and stimulated acid secretion irrespective of the stimulus.