Nilotinib Fumarate

CAS 1304125-88-9

General Information

Nilotinib, also known as AMN107 and sold under the brand name Tasigna, is a medication used to treat Philadelphia chromosome (Ph+)-positive chronic myelogenous leukaemia

A Phase I clinical trial in 2006 showed that this drug was relatively safe and offered significant therapeutic benefits in cases of CML which were found to be resistant to treatment with imatinib (Gleevec), another tyrosine kinase inhibitor used as a first-line treatment for CML.


About the API

Molecular Formula C28H22F3N7O
Molecular Weight 529.5158 gr
Therapeutic category Oncology
Available formulations Oral Solid