Nilotinib Tartrate

CAS 1353151-37-7

Mechanism of action

Nilotinib is an inhibitor of the BCR-ABL kinase.   Nilotinib inhibited the autophosphorylation of the following kinases at IC50 values as indicated: BCR-ABL (20 to 60 nM), PDGFR (69 nM), c-KIT (210 nM), CSF-1R (125 to 250 nM), and DDR1 (3.7 nM)

About the API

Technology Synthetic Organic Chemistry
Therapeutic category Oncology
Available formulations Oral Solid