General Information
In its finished dose, Voclosporin is indicated for the treatment of certain autoimmune diseases, with its primary application being for the management of lupus nephritis. Its mechanism of action inhibits the activation of T cells in the immune system, helping to reduce inflammation and the immune response in conditions like lupus nephritis. Voclosporin is typically used in combination with other medications.
About the API
Systematic name
(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(1R,2R,4E)-1-hydroxy-2-methylhepta-4,6-dienyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
Trade name(s)
Lupkynis
Technology
Fermentation
Molecular Formula
C63H111N11O12
Molecular Weight
1214.646 g/mol
Therapeutic category
Antineoplastic and Immunomodulating Agents
Available formulations
Oral Solid