CAS 486460-32-6

About the API

Therapeutic category Alimentary Tract, Metabol
Regulations EU DMF Flag EU DMF Korea DMF Flag Korea DMF

General Information

Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus.

Reduced inhibition of incretins, increase insulin synthesis and decrease glucagon release in a manner dependant on glucose concentrationsLabel. These effects lead to an overall increase in blood glucose control which is demonstrated by reduced glycosylated hemoglobin.