General Information
Simvastatin belongs to the class of lipid-lowering compounds known as ‘statins’. Generally, statins work by reducing the level of low-density lipoprotein (LDL) cholesterol in the blood by inhibiting the liver enzyme responsible for its production.
About the API
Systematic name
(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-1-naphthalenyl 2,2-dimethylbutanoate
Trade name(s)
Zocor, Synvinolin
Technology
Fermentation
Molecular Formula
C25H38O5
Molecular Weight
418.566 g/mol
Physical properties
White/off-white crystalline powder
Therapeutic category
Lipid lowering
Available formulations
Oral Solid
Oral Solid Long-Acting
Regulations
CEP
EU DMF
Japan DMF
Korea DMF
US DMF
CEP
EU DMF
Japan DMF
Korea DMF
US DMF