General Information
Pravastatin belongs to the family of lipid-lowering compounds known as ‘statins’. Broadly, statins work to reduce the level of low-density lipoprotein (LDL) cholesterol in the blood by inhibiting the liver enzyme responsible for its production.
About the API
Systematic name
Sodium (3R,5R)-3,5-dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-[[(2S)-methylbutanoyl]oxy]-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]heptanoate
Trade name(s)
Pravachol, Selektine, Lipostat
Technology
Fermentation
Molecular Formula
C23H35NaO7
Molecular Weight
446.5 g/mol (anhydrous)
Physical properties
White/off-white crystalline powder
Therapeutic category
Lipid lowering
Available formulations
Oral Solid
Regulations
CEP
EU DMF
Japan DMF
Korea DMF
Other
US DMF
CEP
EU DMF
Japan DMF
Korea DMF
Other
US DMF