General Information
Irbesartan, structurally defined as a nonpeptide tetrazole derivative, is an angiotensin receptor blocker (ARB) used primarily for the treatment of hypertension. Irbesartan can be used alone, but is often prescribed with other medications, e.g. hydrochlorothiazide (marketed as Avalide) to treat hypertension.
About the API
Systematic name
2-Butyl-3-{[2'-(2H-tetrazol-5-yl)-4-biphenylyl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one
Technology
Synthetic
Molecular Formula
C25H28N6O
Molecular Weight
428.529 g/mol
Physical properties
white to off-white crystalline solid
Therapeutic category
Cardiovascular
Available formulations
Oral Solid
Regulations
Canada DMF
CEP
EU DMF
Korea DMF
US DMF
Canada DMF
CEP
EU DMF
Korea DMF
US DMF