Dihydroergotamine Mesylate

CAS 6190-39-2

General Information

Dihydroergotamine mesilate, an ergot alkaloid, is indicated for the acute treatment of migraine headaches with or without aura and the acute treatment of cluster headache episodes. It can be administered orally as a tablet, injected or administered as a nasal spray.

About the API

Systematic name ergotaman-3´,6´,18-trione,9,10-dihydro-12´-hydroxy-2´-methyl-5´-(phenylmethyl)-,(5´α)-, monomethanesulfonate
Trade name(s) D.H.E. 45, Migranal
Technology Plant Extraction
Molecular Formula C33H37N5O5•CH4O3S
Molecular Weight 679.78304 g/mol
Physical properties colorless solution
Therapeutic category Migraine
Available formulations Injectables Nasal Systemic Oral Solid Oral Solid Long-Acting
Regulations CEP Flag CEP EU DMF Flag EU DMF Other Flag Other US DMF Flag US DMF