General Information
Dihydroergotamine mesilate, an ergot alkaloid, is indicated for the acute treatment of migraine headaches with or without aura and the acute treatment of cluster headache episodes. It can be administered orally as a tablet, injected or administered as a nasal spray.
About the API
Systematic name
ergotaman-3´,6´,18-trione,9,10-dihydro-12´-hydroxy-2´-methyl-5´-(phenylmethyl)-,(5´α)-, monomethanesulfonate
Trade name(s)
D.H.E. 45, Migranal
Technology
Plant Extraction
Molecular Formula
C33H37N5O5•CH4O3S
Molecular Weight
679.78304 g/mol
Physical properties
colorless solution
Therapeutic category
Migraine
Available formulations
Injectables
Nasal Systemic
Oral Solid
Oral Solid Long-Acting
Regulations
CEP
EU DMF
Other
US DMF
CEP
EU DMF
Other
US DMF