General Information
Clascoterone, sold under the brand name Winlevi, is a novel antagonist of androgen receptors. Clascoterone works by blocking the androgen receptor signaling cascades that promote acne pathogenesis, such as sebaceous gland proliferation, excess sebum production, and inflammatory pathways.
About the API
Systematic name
[(8R,9S,10R,13S,14S,17R)-17-(2-hydroxyacetyl)-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] propanoate
Trade name(s)
Winlevi
Technology
Synthetic
Molecular Formula
C24H34O5
Molecular Weight
402.5
Therapeutic category
Dermatology
Available formulations
Topical / Dermatological
Regulations
US DMF
US DMF