About the API
Clarithromycin belongs to a class of molecules termed macrolide antibiotics and is used for the treatment of bacterial infections such as pneumonia, bronchitis, and ear, sinus, skin, and throat infections. It is also used for the prophylaxis and treatment of disseminated Mycobacterium avium complex (MAC) infections (a bacterial infection that commonly affects patients with HIV) and in combination with other drugs to target the bacterium H. pylori (a bacterium that causes duodenal ulcers). Clarithromycin inhibits the growth of bacteria by targeting protein synthesis.
Clarithromycin became FDA approved for the treatment of certain bacterial infections under the trade name Biaxin in 1993. It is currently manufactured through large-scale semi-synthetic methods starting with the fermentation product erythromycin. Semi-synthesis is a type of chemical synthesis that uses compounds isolated from abundant, natural sources as starting material.