CAS 1187594-09-7

General Information

Baricitinib is an orally bioavailable inhibitor of Janus kinases 1 and 2 (JAK1/2), with potential anti-inflammatory, immunomodulating and antineoplastic activities. Baricitinib is indicated for treating adults with moderate to severe rheumatoid arthritis who have not responded well enough to or could not tolerate at least one tumor necrosis factor antagonist.

About the API

Systematic name 2-[1-ethylsulfonyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]azetidin-3-yl]acetonitrile
Technology Synthetic
Molecular Formula C16H17N7O2S
Molecular Weight 371.4 g/mol
Therapeutic category Rheumatology
Available formulations Oral Solid