Azacitidine

CAS 320-67-2

General Information

Azacitidine is used to treat myelodysplastic syndromes (MDS), a number of disorders in which not enough healthy blood cells are produced in the bone marrow, leaving patients with low blood counts. In healthy bone marrow, stem cells become red blood cells, white blood cells or platelets. In MDS, this process is dysfunctional. In a significant portion of patients, MDS progresses to a rapidly growing cancer of bone marrow cells called acute myeloid leukemia.

About the API

Systematic name 4-amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one
Trade name(s) Vidaza
Technology High Potent
Molecular Formula C8H12N4O5
Molecular Weight 244.20 g/mol
Physical properties White to off- white powder
Therapeutic category Oncology
Available formulations Injectables
Regulations EU DMF Flag EU DMF US DMF Flag US DMF